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FDA Approves First New Schizophrenia Drug in Over 30 Years

The FDA approved Cobenfy, the first new schizophrenia drug in over 30 years. Unlike older antipsychotics, which alter dopamine, Cobenfy adjusts acetylcholine—a brain chemical affecting memory and attention. This shift may reduce common side effects like weight gain and drowsiness. In trials, only 6% of patients stopped Cobenfy due to side effects, compared to 20-30% with older drugs. Schizophrenia affects about 24 million people globally. Further studies aim to test Cobenfy for Alzheimer's and bipolar disorder.

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